Thorne Advanced Bone Support
vs
Metagenics Fem EstroPlex
Supplement Comparison

  • Vitamin B6 (Pyridoxine): Metagenics Fem EstroPlex has 2.5× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 20 nutrients compared
Bar chart: per-serving label amounts and listed forms for Thorne Advanced Bone Support vs Metagenics Fem EstroPlex.

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Frequently asked questions

Which active ingredients does Thorne Advanced Bone Support have?

  • Vitamin D appears as Cholecalciferol (D3)
  • Vitamin B6 (Pyridoxine) appears as Pyridoxal 5-Phosphate
  • Vitamin B9 (Folate) appears as L-5-Methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Calcium
  • Magnesium
  • Boron

Which active ingredients does Metagenics Fem EstroPlex have?

  • Vitamin C appears as Ascorbic Acid
  • Vitamin E appears as d-Alpha Tocopheryl Succinate
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B5 (Pantothenic Acid) appears as D-Calcium Pantothenate
  • Rutin
  • Blend appears as Proprietary Herbal Extract Blend (Dandelion Chasteberry Valerian Motherwort Stinging Nettle)

Which categories do Thorne Advanced Bone Support and Metagenics Fem EstroPlex belong to?

  • Single Mineral
  • Hormone Support Formula

What health concerns do Thorne Advanced Bone Support and Metagenics Fem EstroPlex address?

  • Healthy Aging & Longevity
  • Hormonal Balance
  • Joint & Bone Health
  • Women's Health

Which product has a higher amount of Vitamin B6 (Pyridoxine) per serving?

  • Metagenics Fem EstroPlex has the highest total amount of Vitamin B6 (Pyridoxine): 50 mg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Thorne Advanced Bone Support: 2 capsules
    • Metagenics Fem EstroPlex: 3 tablets
  • Vitamin D
    • This supplement has 1000 IU
    • Recommended Dietary Allowance in men: 600 IU
    • Recommended Dietary Allowance in women: 600 IU
    • Tolerable Upper Intake Level: 4000 IU
  • Vitamin B6 (Pyridoxine)
    • This supplement has 20 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 166.6 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B12 (Cobalamin)
    • This supplement has 50 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established
  • Calcium
    • This supplement has 300 mg
    • Recommended Dietary Allowance in men: 1000 mg
    • Recommended Dietary Allowance in women: 1000 mg
    • Tolerable Upper Intake Level: 2500 mg
  • Vitamin C
    • This supplement has 300 mg
    • Recommended Dietary Allowance in men: 90 mg
    • Recommended Dietary Allowance in women: 75 mg
    • Tolerable Upper Intake Level: 2000 mg
  • Vitamin E
    • This supplement has 67 mg
    • Recommended Dietary Allowance in men: 15 mg
    • Recommended Dietary Allowance in women: 15 mg
    • Tolerable Upper Intake Level: 1000 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 50 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B5 (Pantothenic Acid)
    • This supplement has 300 mg
    • Adequate Intake in men: 5 mg
    • Adequate Intake in women: 5 mg
    • Tolerable Upper Intake Level: Not established

Last updated: February 17, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
  • Questions? Read our Frequently Asked Questions or contact us, we’re here to help.
  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team