Thorne 5-MTHF 1 mg
vs
Metagenics MethylCare
Supplement Comparison

  • Vitamin B9 (Folate): Thorne 5-MTHF 1 mg has 28% more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 16 nutrients compared
Bar chart: per-serving label amounts and listed forms for Thorne 5-MTHF 1 mg vs Metagenics MethylCare.

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Frequently asked questions

Which active ingredients does Thorne 5-MTHF 1 mg have?

  • Vitamin B9 (Folate) appears as L-5-Methyltetrahydrofolate

Which active ingredients does Metagenics MethylCare have?

  • Vitamin B2 (Riboflavin) appears as Riboflavin
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B9 (Folate) appears as Calcium L-5-Methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Zinc appears as Zinc Citrate
  • Manganese appears as Manganese Citrate
  • Molybdenum appears as Molybdenum Glycinate
  • Betaine Hydrochloride
  • N-Acetyl-L-Cysteine (NAC)

Which categories do Thorne 5-MTHF 1 mg and Metagenics MethylCare belong to?

  • Methylation Formula
  • Prenatal Formula
  • Single Vitamin

What health concerns do Thorne 5-MTHF 1 mg and Metagenics MethylCare address?

  • Brain, Focus & Cognitive Function
  • General Health
  • Heart & Cardiovascular Health
  • Methylation Support
  • Mood Support
  • Pregnancy Support
  • Energy & Metabolism
  • Liver & Detox Support

Which product has a higher amount of Vitamin B9 (Folate) per serving?

  • Thorne 5-MTHF 1 mg has the highest total amount of Vitamin B9 (Folate): 1700 mcg DFE per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Thorne 5-MTHF 1 mg: 1 capsule
    • Metagenics MethylCare: 2 capsules
  • Vitamin B9 (Folate)
    • This supplement has 1700 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B2 (Riboflavin)
    • This supplement has 1.6 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B6 (Pyridoxine)
    • This supplement has 25 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 1330 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B12 (Cobalamin)
    • This supplement has 1000 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established
  • Zinc
    • This supplement has 1.5 mg
    • Recommended Dietary Allowance in men: 11 mg
    • Recommended Dietary Allowance in women: 8 mg
    • Tolerable Upper Intake Level: 40 mg
  • Manganese
    • This supplement has 0.4 mg
    • Adequate Intake in men: 2.3 mg
    • Adequate Intake in women: 1.8 mg
    • Tolerable Upper Intake Level: 11 mg

Last updated: February 21, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
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  • Author: VIOscan Research Team