Optimum Nutrition OPTI-MEN
vs
Natural Factors Active B Complex
Supplement Comparison

  • Vitamin B12 (Cobalamin): Natural Factors Active B Complex has 20× more
  • Vitamin B9 (Folate): Natural Factors Active B Complex has 70% more
  • Vitamin B6 (Pyridoxine): Natural Factors Active B Complex has 13× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 49 nutrients compared
Bar chart: per-serving label amounts and listed forms for Optimum Nutrition OPTI-MEN vs Natural Factors Active B Complex.

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Frequently asked questions

Which active ingredients does Optimum Nutrition OPTI-MEN have?

  • Vitamin A
  • Vitamin C
  • Vitamin D
  • Vitamin E
  • Vitamin K
  • Vitamin B1 (Thiamin)
  • Vitamin B2 (Riboflavin)
  • Vitamin B3 (Niacin)
  • Vitamin B6 (Pyridoxine)
  • Vitamin B9 (Folate)
  • Vitamin B12 (Cobalamin)
  • Vitamin B7 (Biotin)
  • Vitamin B5 (Pantothenic Acid)
  • Alpha-Carotene
  • PABA
  • Calcium
  • Iodine
  • Magnesium
  • Zinc
  • Selenium appears as L-Selenomethionine
  • Chromium appears as Chromium nicotinate glycinate chelate
  • Molybdenum appears as Molybdenum A.A. chelate
  • Boron appears as Boron citrate
  • Vanadium appears as Vanadium citrate
  • Lutein
  • Lycopene
  • Inositol
  • Alpha Lipoic Acid
  • Zeaxanthin
  • Amino Men Blend by Optimum Nutrition
  • Phyto Men Blend by Optimum Nutrition
  • Viri Men Blend by Optimum Nutrition
  • Enzyme Blend by Optimum Nutrition
  • Cryptoxanthin

Which active ingredients does Natural Factors Active B Complex have?

  • Vitamin B1 (Thiamin) appears as Thiamin HCl and Benfotiamine
  • Vitamin B2 (Riboflavin) appears as Riboflavin 5-Phosphate Sodium
  • Vitamin B3 (Niacin) appears as Inositol Hexanicotinate
  • Vitamin B6 (Pyridoxine) appears as Pyridoxal 5-Phosphate
  • Vitamin B9 (Folate) appears as Quatrefolic (6S)-5-MTHF Glucosamine Salt
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Vitamin B7 (Biotin) appears as D-Biotin
  • Vitamin B5 (Pantothenic Acid) appears as D-Calcium Pantothenate
  • Choline appears as Choline Citrate
  • Inositol

Which categories do Optimum Nutrition OPTI-MEN and Natural Factors Active B Complex belong to?

  • Multivitamin
  • B-Complex Formula

What health concerns do Optimum Nutrition OPTI-MEN and Natural Factors Active B Complex address?

  • General Health
  • Men's Health
  • Brain, Focus & Cognitive Function
  • Energy & Metabolism
  • Methylation Support

Which product has a higher amount of Vitamin B12 (Cobalamin) per serving?

  • Natural Factors Active B Complex has the highest total amount of Vitamin B12 (Cobalamin): 500 mcg per serving

Which product has a higher amount of Vitamin B9 (Folate) per serving?

  • Natural Factors Active B Complex has the highest total amount of Vitamin B9 (Folate): 680 mcg DFE per serving

Which product has a higher amount of Vitamin B6 (Pyridoxine) per serving?

  • Natural Factors Active B Complex has the highest total amount of Vitamin B6 (Pyridoxine): 25 mg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Optimum Nutrition OPTI-MEN: 3 tablets
    • Natural Factors Active B Complex: 1 capsule
  • Vitamin A
    • This supplement has 1500 mcg RAE
    • Recommended Dietary Allowance in men: 900 mcg RAE
    • Recommended Dietary Allowance in women: 700 mcg RAE
    • Tolerable Upper Intake Level: 3000 mcg RAE
  • Vitamin C
    • This supplement has 60 mg
    • Recommended Dietary Allowance in men: 90 mg
    • Recommended Dietary Allowance in women: 75 mg
    • Tolerable Upper Intake Level: 2000 mg
  • Vitamin D
    • This supplement has 400 IU
    • Recommended Dietary Allowance in men: 600 IU
    • Recommended Dietary Allowance in women: 600 IU
    • Tolerable Upper Intake Level: 4000 IU
  • Vitamin E
    • This supplement has 100 mg
    • Recommended Dietary Allowance in men: 15 mg
    • Recommended Dietary Allowance in women: 15 mg
    • Tolerable Upper Intake Level: 1000 mg
  • Vitamin K
    • This supplement has 75 mcg
    • Adequate Intake in men: 120 mcg
    • Adequate Intake in women: 90 mcg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B1 (Thiamin)
    • This supplement has 1.5 mg
    • Recommended Dietary Allowance in men: 1.2 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B1 (Thiamin)
    • This supplement has 30 mg
    • Recommended Dietary Allowance in men: 1.2 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B2 (Riboflavin)
    • This supplement has 10 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B3 (Niacin)
    • This supplement has 100 mg
    • Recommended Dietary Allowance in men: 16 mg
    • Recommended Dietary Allowance in women: 14 mg
    • Tolerable Upper Intake Level: 35 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 25 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 680 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B12 (Cobalamin)
    • This supplement has 500 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established

Last updated: February 18, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
  • Questions? Read our Frequently Asked Questions or contact us, we’re here to help.
  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team