NaturesPlus Hema-Plex
vs
Metagenics Fem EstroPlex
Supplement Comparison

  • Vitamin C: same total amount on both labels
  • Vitamin E: Metagenics Fem EstroPlex has 3.4× more
  • Vitamin B6 (Pyridoxine): Metagenics Fem EstroPlex has 2.0× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 36 nutrients compared
Bar chart: per-serving label amounts and listed forms for NaturesPlus Hema-Plex vs Metagenics Fem EstroPlex.

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Frequently asked questions

Which active ingredients does NaturesPlus Hema-Plex have?

  • Vitamin C appears as Proprietary Esterified Complex (ascorbyl palmitate, ascorbic acid, magnesium ascorbate, potassium ascorbate, zinc ascorbate)
  • Vitamin E appears as dl-Alpha Tocopheryl Acetate
  • Vitamin B1 (Thiamin) appears as Thiamin HCl
  • Vitamin B2 (Riboflavin) appears as Riboflavin
  • Vitamin B3 (Niacin) appears as Niacinamide
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B9 (Folate) appears as Calcium-L-5-methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Vitamin B5 (Pantothenic Acid) appears as Calcium Pantothenate
  • Calcium appears as Calcium amino acid chelate/complex
  • Iron appears as Iron amino acid chelate/complex
  • Zinc appears as Zinc Monomethionine
  • Selenium appears as Albion Amino Acid Complex
  • Copper appears as Copper Amino Acid Chelate
  • Manganese appears as Manganese Amino Acid Chelate
  • L-Cysteine
  • Black Pepper Fruit Extract appears as BioPerine Black Pepper Fruit Extract
  • Beet (Beta vulgaris) Root
  • Blend appears as Proanthoplex Proprietary Proanthocyanidin/Bioflavonoid Complex (Bioflavonoids, Bilberry fruit, Wild Black Raspberry seed, Green Tea leaf, Red Raspberry fruit)

Which active ingredients does Metagenics Fem EstroPlex have?

  • Vitamin C appears as Ascorbic Acid
  • Vitamin E appears as d-Alpha Tocopheryl Succinate
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B5 (Pantothenic Acid) appears as D-Calcium Pantothenate
  • Rutin
  • Blend appears as Proprietary Herbal Extract Blend (Dandelion Chasteberry Valerian Motherwort Stinging Nettle)

Which categories do NaturesPlus Hema-Plex and Metagenics Fem EstroPlex belong to?

  • Multivitamin
  • Hormone Support Formula

What health concerns do NaturesPlus Hema-Plex and Metagenics Fem EstroPlex address?

  • Antioxidant Support
  • Women's Health

Which product has a higher amount of Vitamin C per serving?

  • Both products list the same total amount of Vitamin C per serving

Which product has a higher amount of Vitamin E per serving?

  • Metagenics Fem EstroPlex has the highest total amount of Vitamin E: 67 mg per serving

Which product has a higher amount of Vitamin B6 (Pyridoxine) per serving?

  • Metagenics Fem EstroPlex has the highest total amount of Vitamin B6 (Pyridoxine): 50 mg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • NaturesPlus Hema-Plex: 1 tablet
    • Metagenics Fem EstroPlex: 3 tablets
  • Vitamin C
    • This supplement has 300 mg
    • Recommended Dietary Allowance in men: 90 mg
    • Recommended Dietary Allowance in women: 75 mg
    • Tolerable Upper Intake Level: 2000 mg
  • Vitamin E
    • This supplement has 20 mg
    • Recommended Dietary Allowance in men: 15 mg
    • Recommended Dietary Allowance in women: 15 mg
    • Tolerable Upper Intake Level: 1000 mg
  • Vitamin B1 (Thiamin)
    • This supplement has 25 mg
    • Recommended Dietary Allowance in men: 1.2 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B2 (Riboflavin)
    • This supplement has 25 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B3 (Niacin)
    • This supplement has 50 mg
    • Recommended Dietary Allowance in men: 16 mg
    • Recommended Dietary Allowance in women: 14 mg
    • Tolerable Upper Intake Level: 35 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 25 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin C
    • This supplement has 300 mg
    • Recommended Dietary Allowance in men: 90 mg
    • Recommended Dietary Allowance in women: 75 mg
    • Tolerable Upper Intake Level: 2000 mg
  • Vitamin E
    • This supplement has 67 mg
    • Recommended Dietary Allowance in men: 15 mg
    • Recommended Dietary Allowance in women: 15 mg
    • Tolerable Upper Intake Level: 1000 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 50 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B5 (Pantothenic Acid)
    • This supplement has 300 mg
    • Adequate Intake in men: 5 mg
    • Adequate Intake in women: 5 mg
    • Tolerable Upper Intake Level: Not established

Last updated: February 20, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
  • Questions? Read our Frequently Asked Questions or contact us, we’re here to help.
  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team