Life Extension Melatonin IR/XR
vs
Metagenics MetaSleep™
Supplement Comparison

  • Melatonin: Metagenics MetaSleep™ has 2.0× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 4 nutrients compared
Bar chart: per-serving label amounts and listed forms for Life Extension Melatonin IR/XR vs Metagenics MetaSleep™.

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Frequently asked questions

Which active ingredients does Life Extension Melatonin IR/XR have?

  • Melatonin appears as MicroActive Melatonin

Which active ingredients does Metagenics MetaSleep™ have?

  • Melatonin
  • Kava (Piper methysticum) appears as Kava (Piper methysticum) Root Extract standardized to 10% total kavalactones

Which categories do Life Extension Melatonin IR/XR and Metagenics MetaSleep™ belong to?

  • Sleep Formula

What health concerns do Life Extension Melatonin IR/XR and Metagenics MetaSleep™ address?

  • Healthy Aging & Longevity
  • Hormonal Balance
  • Sleep Quality

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Life Extension Melatonin IR/XR: 1 capsule
    • Metagenics MetaSleep™: 2 capsules

Last updated: February 13, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
  • Questions? Read our Frequently Asked Questions or contact us, we’re here to help.
  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team