Life Extension Immune Senescence Protection Formula
vs
Metagenics Bone Builder® Prime
Supplement Comparison

  • Calcium: Metagenics Bone Builder® Prime has 3.8× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 12 nutrients compared
Bar chart: per-serving label amounts and listed forms for Life Extension Immune Senescence Protection Formula vs Metagenics Bone Builder® Prime.

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Frequently asked questions

Which active ingredients does Life Extension Immune Senescence Protection Formula have?

  • Calcium appears as Calcium Carbonate
  • Reishi (Ganoderma lucidum) Mushroom appears as Shell-broken Reishi Mushroom Spore
  • Pu-erh Tea Extract
  • Cistanche Extract

Which active ingredients does Metagenics Bone Builder® Prime have?

  • Vitamin D appears as Cholecalciferol (D3)
  • Calcium appears as Calcium (MCHC, dicalcium phosphate)
  • Phosphorus appears as Phosphorus (MCHC, dicalcium phosphate)
  • Microcrystalline Hydroxyapatite Concentrate (MCHC)
  • Ipriflavone

Which categories do Life Extension Immune Senescence Protection Formula and Metagenics Bone Builder® Prime belong to?

  • Herbal Extract
  • Mushroom Extract
  • Joint Formula

What health concerns do Life Extension Immune Senescence Protection Formula and Metagenics Bone Builder® Prime address?

  • Anti-Inflammatory Support
  • Healthy Aging & Longevity
  • Immune System Support
  • Joint & Bone Health

Which product has a higher amount of Calcium per serving?

  • Metagenics Bone Builder® Prime has the highest total amount of Calcium: 660 mg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Life Extension Immune Senescence Protection Formula: 2 tablets
    • Metagenics Bone Builder® Prime: 3 tablets
  • Calcium
    • This supplement has 175 mg
    • Recommended Dietary Allowance in men: 1000 mg
    • Recommended Dietary Allowance in women: 1000 mg
    • Tolerable Upper Intake Level: 2500 mg
  • Vitamin D
    • This supplement has 600 IU
    • Recommended Dietary Allowance in men: 600 IU
    • Recommended Dietary Allowance in women: 600 IU
    • Tolerable Upper Intake Level: 4000 IU
  • Calcium
    • This supplement has 660 mg
    • Recommended Dietary Allowance in men: 1000 mg
    • Recommended Dietary Allowance in women: 1000 mg
    • Tolerable Upper Intake Level: 2500 mg
  • Phosphorus
    • This supplement has 380 mg
    • Recommended Dietary Allowance in men: 700 mg
    • Recommended Dietary Allowance in women: 700 mg
    • Tolerable Upper Intake Level: 4000 mg

Last updated: February 13, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
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  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team