Life Extension BioActive Complete B-Complex
vs
Metagenics SeroSyn
Supplement Comparison

  • Vitamin B12 (Cobalamin): Life Extension BioActive Complete B-Complex has 20% more
  • Vitamin B9 (Folate): Life Extension BioActive Complete B-Complex has 23% more
  • Vitamin B6 (Pyridoxine): Life Extension BioActive Complete B-Complex has 10× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 24 nutrients compared
Bar chart: per-serving label amounts and listed forms for Life Extension BioActive Complete B-Complex vs Metagenics SeroSyn.

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Frequently asked questions

Which active ingredients does Life Extension BioActive Complete B-Complex have?

  • Vitamin B1 (Thiamin) appears as Thiamin HCl
  • Vitamin B2 (Riboflavin) appears as Riboflavin and Riboflavin 5-Phosphate
  • Vitamin B3 (Niacin) appears as Niacinamide
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl and Pyridoxal 5-Phosphate
  • Vitamin B9 (Folate) appears as L-5-Methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Vitamin B7 (Biotin)
  • Vitamin B5 (Pantothenic Acid) appears as Calcium Pantothenate
  • PABA
  • Calcium appears as D-Calcium Pantothenate and Dicalcium Phosphate
  • Inositol

Which active ingredients does Metagenics SeroSyn have?

  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B9 (Folate) appears as Calcium-L-5-methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • 5-Hydroxytryptophan
  • Asian Ginseng Extract appears as Asian Ginseng (Panax ginseng) Root Extract standardized to 8% ginsenosides
  • L-Theanine
  • Chinese Skullcap (Scutellaria baicalensis) appears as Chinese Skullcap (Scutellaria baicalensis) Root Extract standardized to 30% flavones

Which categories do Life Extension BioActive Complete B-Complex and Metagenics SeroSyn belong to?

  • B-Complex Formula
  • Single Mineral

What health concerns do Life Extension BioActive Complete B-Complex and Metagenics SeroSyn address?

  • Brain, Focus & Cognitive Function
  • Energy & Metabolism
  • Mood Support
  • Stress Management

Which product has a higher amount of Vitamin B12 (Cobalamin) per serving?

  • Life Extension BioActive Complete B-Complex has the highest total amount of Vitamin B12 (Cobalamin): 300 mcg per serving

Which product has a higher amount of Vitamin B9 (Folate) per serving?

  • Life Extension BioActive Complete B-Complex has the highest total amount of Vitamin B9 (Folate): 680 mcg DFE per serving

Which product has a higher amount of Vitamin B6 (Pyridoxine) per serving?

  • Life Extension BioActive Complete B-Complex has the highest total amount of Vitamin B6 (Pyridoxine): 100 mg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • Life Extension BioActive Complete B-Complex: 2 capsules
    • Metagenics SeroSyn: 1 capsule
  • Vitamin B1 (Thiamin)
    • This supplement has 100 mg
    • Recommended Dietary Allowance in men: 1.2 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B2 (Riboflavin)
    • This supplement has 75 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B3 (Niacin)
    • This supplement has 100 mg
    • Recommended Dietary Allowance in men: 16 mg
    • Recommended Dietary Allowance in women: 14 mg
    • Tolerable Upper Intake Level: 35 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 100 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 680 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B12 (Cobalamin)
    • This supplement has 300 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B6 (Pyridoxine)
    • This supplement has 10 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 555 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE
  • Vitamin B12 (Cobalamin)
    • This supplement has 250 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established

Last updated: February 18, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
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  • Author: VIOscan Research Team