21st Century Vitamin B-12 5000 mcg
vs
Metagenics Vitamin B-Complex
Supplement Comparison

  • Vitamin B12 (Cobalamin): 21st Century Vitamin B-12 5000 mcg has 20× more
  • The image below shows:
    • Side-by-side charts with label nutrient amounts, per serving
    • Nutrient forms as listed on the label
    • 21 nutrients compared
Bar chart: per-serving label amounts and listed forms for 21st Century Vitamin B-12 5000 mcg vs Metagenics Vitamin B-Complex.

Try the VIOscan dashboard demo for free

Build comparison charts in seconds – no signup or card needed

This is a free preview of the $9.99/month premium dashboard

Use the interactive demo with multivitamins samples

Try Free Demo

Frequently asked questions

Which active ingredients does 21st Century Vitamin B-12 5000 mcg have?

  • Vitamin B12 (Cobalamin) appears as Cyanocobalamin

Which active ingredients does Metagenics Vitamin B-Complex have?

  • Vitamin C appears as Ascorbic Acid
  • Vitamin B1 (Thiamin) appears as Thiamin Mononitrate
  • Vitamin B2 (Riboflavin)
  • Vitamin B3 (Niacin) appears as Niacinamide and Niacin
  • Vitamin B6 (Pyridoxine) appears as Pyridoxine HCl
  • Vitamin B9 (Folate) appears as Calcium L-5-Methyltetrahydrofolate
  • Vitamin B12 (Cobalamin) appears as Methylcobalamin
  • Vitamin B7 (Biotin)
  • Vitamin B5 (Pantothenic Acid) appears as D-Calcium Pantothenate
  • Choline appears as Choline Bitartrate
  • PABA
  • Inositol appears as Myo-Inositol

Which categories do 21st Century Vitamin B-12 5000 mcg and Metagenics Vitamin B-Complex belong to?

  • Single Vitamin
  • B-Complex Formula

What health concerns do 21st Century Vitamin B-12 5000 mcg and Metagenics Vitamin B-Complex address?

  • General Health
  • Energy & Metabolism

Which product has a higher amount of Vitamin B12 (Cobalamin) per serving?

  • 21st Century Vitamin B-12 5000 mcg has the highest total amount of Vitamin B12 (Cobalamin): 5000 mcg per serving

How do the serving sizes compare between the two supplements?

  • Serving size:
    • 21st Century Vitamin B-12 5000 mcg: 1 tablet
    • Metagenics Vitamin B-Complex: 1 tablet
  • Vitamin B12 (Cobalamin)
    • This supplement has 5000 mcg
    • Recommended Dietary Allowance in men: 2.4 mcg
    • Recommended Dietary Allowance in women: 2.4 mcg
    • Tolerable Upper Intake Level: Not established
  • Vitamin C
    • This supplement has 125 mg
    • Recommended Dietary Allowance in men: 90 mg
    • Recommended Dietary Allowance in women: 75 mg
    • Tolerable Upper Intake Level: 2000 mg
  • Vitamin B1 (Thiamin)
    • This supplement has 14 mg
    • Recommended Dietary Allowance in men: 1.2 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B2 (Riboflavin)
    • This supplement has 16 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.1 mg
    • Tolerable Upper Intake Level: Not established
  • Vitamin B3 (Niacin)
    • This supplement has 200 mg
    • Recommended Dietary Allowance in men: 16 mg
    • Recommended Dietary Allowance in women: 14 mg
    • Tolerable Upper Intake Level: 35 mg
  • Vitamin B6 (Pyridoxine)
    • This supplement has 22 mg
    • Recommended Dietary Allowance in men: 1.3 mg
    • Recommended Dietary Allowance in women: 1.3 mg
    • Tolerable Upper Intake Level: 100 mg
  • Vitamin B9 (Folate)
    • This supplement has 665 mcg DFE
    • Recommended Dietary Allowance in men: 400 mcg DFE
    • Recommended Dietary Allowance in women: 400 mcg DFE
    • Tolerable Upper Intake Level: 1000 mcg DFE

Last updated: February 5, 2026

  • Sources & Methodology: Nutrient data and forms are taken directly from Supplement Facts labels. Reviewed and standardized by the VIOscan Research Team. Learn more on the Methodology page.
  • We show the Recommended Dietary Allowance (RDA) when available. If no RDA exists, we show the Adequate Intake (AI). Tolerable Upper Intake Levels (UL) are used for upper limits. Unless otherwise noted, RDAs shown correspond to healthy adults aged 19–50 years and are sex-specific. Separate values exist for 51–70 years and >70 years, and pregnancy and lactation are excluded. All values come from the Dietary Reference Intakes (DRIs) published by the National Academies of Sciences, Engineering, and Medicine (NASEM), Food and Nutrition Board (FNB).
  • Transparency: We’re funded by our users. We don’t have sponsors or affiliate links, and we don’t sell supplements.
  • Editorial standards: we provide independent, impartial and objective data analysis.
  • This analysis is for educational purposes only. It is not a substitute for medical advice.
  • Questions? Read our Frequently Asked Questions or contact us, we’re here to help.
  • See an error? Report it through our Contact page.
  • Author: VIOscan Research Team